hepatic steatosis — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TD0093	Oil Red O		Others
	The dry dye Oil red O is used for the preparation of a staining solution that can be used for the detection of lipids in histological cryo sections.		Others
T12580	PTUPB		COX , Epoxide Hydrolase
	PTUPB is a potent and dual inhibitor of sEH and COX-2 enzymes(IC50 of 0.9 nM and 1.26 μM, respectively).		COX , Epoxide Hydrolase
T7992	4-Hydroxyflavanone		NO Synthase
	4-Hydroxyflavanone is a natural product, shows full vasorelaxing effects		NO Synthase
T3888	Scopolin	Murrayin,Scopoloside	Sirtuin
	Scopolin (Scopoloside) formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, and this compound may be a potent agent for...		Sirtuin
T0746	Orotic acid	Vitamin B13,6-Carboxyuracil	Nucleoside Antimetabolite/Analog , Dehydrogenase , Endogenous Metabolite
	Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism.
T3271	Orotic acid zinc	Orotic acid zinc salt dihydrate,Zinc Orotate	Nucleoside Antimetabolite/Analog , Others , Endogenous Metabolite
	Orotic acid zinc (Zinc Orotate) salt dihydrate is an intermediate product in pyrimidine synthesis.
TN6751	1-HEXACOSANOL		NPC1L1 , AMPK
	Hexacosanol activates AMPK and hepatic autophagy and inhibits SREBP2, resulting in hypocholesterolemic activities and improvement of hepatic steatosis.		NPC1L1 , AMPK
T15779	LP-533401 hydrochloride		5-HT Receptor
	LP-533401 hydrochloride is a peripheral Tph inhibitor that cannot cross the blood-brain barrier that inhibits 5-hydroxytryptamine synthesis and can be used to study periodontal disease and hepatic steatosis.		5-HT Receptor
T60004	SRI-37330		Others
	SRI-37330 inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis.		Others
T60033	SBI993		Others
	SBI993 is an analog of SBI-477 and can be used as a biomarker to confirm the expected action of MondoA target gene expression in vivo. SBI993 reduces muscle TAG levels and hepatic steatosis.		Others
T77245	Mannan		Endogenous Metabolite
	Mannan is isolated from algae, mushrooms, yeast and higher plants and acts as an immunomodulator.Mannan inhibits the pro-inflammatory activity of hepatic macrophages (M1 lineage) with protective effects against many live...		Endogenous Metabolite
T9186	Ervogastat	PF-06865571	Transferase
	Ervogastat (PF-06865571) is a potent and well-tolerated diacylglycerol acyltransferase 2 inhibitor. Ervogastat reduces steatosis and hepatic triglyceride levels in non-alcoholic steatohepatitis (NASH).		Transferase
T23097	O-1602	O1602,O 1602	Cannabinoid Receptor , Calcium Channel
	O-1602 is a novel GPR55 agonist, an atypical cannabinoid associated with the central nervous system and obesity, and is a candidate compound for the treatment of cystitis.O-1602 promotes hepatic steatosis through GPR55 a...		Cannabinoid Receptor , Calcium Channel
T6S0221	Eriocitrin	eriodictyol 7-rutinoside,Eriodictyol-7-O-Rutinoside,Eriodictioside,Eriodictyol glycoside	Apoptosis , Carbonic Anhydrase
	1. Eriocitrin (Eriodictyol-7-O-Rutinoside) is powerful antioxidative flavonoid; (1) Prevents oxidative damages caused by acute exercise-induced oxidative stress.(2) Lipid-lowering effects in a rat model of high-fat diet....		Apoptosis , Carbonic Anhydrase
T30784	Cedrene	AI3-51328,AI3 51328,AI351328
	Cedrene can regulate hepatic steatosis via the cAMP-PKA pathway.
T68974	MHY553
	MHY 553 is a PPARα agonist that improved aged-induced hepatic steatosis.
T35441	Tripalmitolein
	Tripalmitolein is a triacylglycerol that contains palmitoleic acid at the sn-1, sn-2, and sn-3 positions. It reduces red blood cell deformability in a concentration-dependent manner in a Reid's filtration assay. Hepatic ...
T36860	C22 Sphingomyelin (d18:1/22:0)	C22 Sphingomyelin (d18:1/22:0)
	C22 Sphingomyelin is a naturally occurring form of sphingomyelin . Plasma levels of C22 sphingomyelin positively correlate with hepatic steatosis severity in patients with chronic hepatitis C virus (HCV). C22 Sphingomyel...
T72889	FXR agonist 4
	FXR agonist 4 with an EC 50 value of 1.05 μM. FXR agonist 4 effectively improves hyperlipidemia, hepatic steatosis, insulin resistance and hepatic inflammation in DIO mice. FXR agonist 4 can be used for the research of ...
T35444	1-Pentadecanoyl-rac-glycerol
	1-Pentadecanoyl-rac-glycerol is a monoacylglycerol that contains pentadecanoic acid at the sn-1 position. It has been found in wheat bran extracts.1 1-Pentadecanoyl-rac-glycerol levels are increased in a HepaRG cell-base...